KEGG   Mus musculus (house mouse): 13436
Entry
13436             CDS       T01002                                 
Symbol
Dnmt3b, MmuIIIB
Name
(RefSeq) DNA methyltransferase 3B
  KO
K17399  DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00270  Cysteine and methionine metabolism
mmu01100  Metabolic pathways
mmu05206  MicroRNAs in cancer
Module
mmu_M00035  Methionine degradation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    13436 (Dnmt3b)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    13436 (Dnmt3b)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    13436 (Dnmt3b)
   03032 DNA replication proteins [BR:mmu03032]
    13436 (Dnmt3b)
   03036 Chromosome and associated proteins [BR:mmu03036]
    13436 (Dnmt3b)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     13436 (Dnmt3b)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  Zinc finger
   Cys4 GATA-factors
    13436 (Dnmt3b)
DNA replication proteins [BR:mmu03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    13436 (Dnmt3b)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    13436 (Dnmt3b)
SSDB
Motif
Pfam: ADD_DNMT3 ADDz_Dnmt3b DNA_methylase PWWP
Other DBs
NCBI-GeneID: 13436
NCBI-ProteinID: NP_001003961
MGI: 1261819
Ensembl: ENSMUSG00000027478
UniProt: O88509 Q3KR45
Structure
Position
2:153491332..153529650
AA seq 859 aa
MKGDSRHLNEEEGASGYEECIIVNGNFSDQSSDTKDAPSPPVLEAICTEPVCTPETRGRR
SSSRLSKREVSSLLNYTQDMTGDGDRDDEVDDGNGSDILMPKLTRETKDTRTRSESPAVR
TRHSNGTSSLERQRASPRITRGRQGRHHVQEYPVEFPATRSRRRRASSSASTPWSSPASV
DFMEEVTPKSVSTPSVDLSQDGDQEGMDTTQVDAESRDGDSTEYQDDKEFGIGDLVWGKI
KGFSWWPAMVVSWKATSKRQAMPGMRWVQWFGDGKFSEISADKLVALGLFSQHFNLATFN
KLVSYRKAMYHTLEKARVRAGKTFSSSPGESLEDQLKPMLEWAHGGFKPTGIEGLKPNKK
QPVVNKSKVRRSDSRNLEPRRRENKSRRRTTNDSAASESPPPKRLKTNSYGGKDRGEDEE
SRERMASEVTNNKGNLEDRCLSCGKKNPVSFHPLFEGGLCQSCRDRFLELFYMYDEDGYQ
SYCTVCCEGRELLLCSNTSCCRCFCVECLEVLVGAGTAEDAKLQEPWSCYMCLPQRCHGV
LRRRKDWNMRLQDFFTTDPDLEEFEPPKLYPAIPAAKRRPIRVLSLFDGIATGYLVLKEL
GIKVEKYIASEVCAESIAVGTVKHEGQIKYVNDVRKITKKNIEEWGPFDLVIGGSPCNDL
SNVNPARKGLYEGTGRLFFEFYHLLNYTRPKEGDNRPFFWMFENVVAMKVNDKKDISRFL
ACNPVMIDAIKVSAAHRARYFWGNLPGMNRPVMASKNDKLELQDCLEFSRTAKLKKVQTI
TTKSNSIRQGKNQLFPVVMNGKDDVLWCTELERIFGFPAHYTDVSNMGRGARQKLLGRSW
SVPVIRHLFAPLKDYFACE
NT seq 2580 nt   +upstreamnt  +downstreamnt
atgaagggagacagcagacatctgaatgaagaagagggtgccagcgggtatgaggagtgc
attatcgttaatgggaacttcagtgaccagtcctcagacacgaaggatgctccctcaccc
ccagtcttggaggcaatctgcacagagccagtctgcacaccagagaccagaggccgcagg
tcaagctcccggctgtctaagagggaggtctccagccttctgaattacacgcaggacatg
acaggagatggagacagagatgatgaagtagatgatgggaatggctctgatattctaatg
ccaaagctcacccgtgagaccaaggacaccaggacgcgctctgaaagcccggctgtccga
acccgacatagcaatgggacctccagcttggagaggcaaagagcctcccccagaatcacc
cgaggtcggcagggccgccaccatgtgcaggagtaccctgtggagtttccggctaccagg
tctcggagacgtcgagcatcatcttcagcaagcacgccatggtcatcccctgccagcgtc
gacttcatggaagaagtgacacctaagagcgtcagtaccccatcagttgacttgagccag
gatggagatcaggagggtatggataccacacaggtggatgcagagagcagagatggagac
agcacagagtatcaggatgataaagagtttggaataggtgacctcgtgtggggaaagatc
aagggcttctcctggtggcctgccatggtggtgtcctggaaagccacctccaagcgacag
gccatgcccggaatgcgctgggtacagtggtttggtgatggcaagttttctgagatctct
gctgacaaactggtggctctggggctgttcagccagcactttaatctggctaccttcaat
aagctggtttcttataggaaggccatgtaccacactctggagaaagccagggttcgagct
ggcaagaccttctccagcagtcctggagagtcactggaggaccagctgaagcccatgctg
gagtgggcccacggtggcttcaagcctactgggatcgagggcctcaaacccaacaagaag
caaccagtggttaataagtcgaaggtgcgtcgttcagacagtaggaacttagaacccagg
agacgcgagaacaaaagtcgaagacgcacaaccaatgactctgctgcttctgagtccccc
ccacccaagcgcctcaagacaaatagctatggcgggaaggaccgaggggaggatgaggag
agccgagaacggatggcttctgaagtcaccaacaacaagggcaatctggaagaccgctgt
ttgtcctgtggaaagaagaaccctgtgtccttccaccccctctttgagggtgggctctgt
cagagttgccgggatcgcttcctagagctcttctacatgtatgatgaggacggctatcag
tcctactgcaccgtgtgctgtgagggccgtgaactgctgctgtgcagtaacacaagctgc
tgcagatgcttctgtgtggagtgtctggaggtgctggtgggcgcaggcacagctgaggat
gccaagctgcaggaaccctggagctgctatatgtgcctccctcagcgctgccatggggtc
ctccgacgcaggaaagattggaacatgcgcctgcaagacttcttcactactgatcctgac
ctggaagaatttgagccacccaagttgtacccagcaattcctgcagccaaaaggaggccc
attagagtcctgtctctgtttgatggaattgcaacggggtacttggtgctcaaggagttg
ggtattaaagtggaaaagtacattgcctccgaagtctgtgcagagtccatcgctgtggga
actgttaagcatgaaggccagatcaaatatgtcaatgacgtccggaaaatcaccaagaaa
aatattgaagagtggggcccgttcgacttggtgattggtggaagcccatgcaatgatctc
tctaacgtcaatcctgcccgcaaaggtttatatgagggcacaggaaggctcttcttcgag
ttttaccacttgctgaattatacccgccccaaggagggcgacaaccgtccattcttctgg
atgttcgagaatgttgtggccatgaaagtgaatgacaagaaagacatctcaagattcctg
gcatgtaacccagtgatgatcgatgccatcaaggtgtctgctgctcacagggcccggtac
ttctggggtaacctacccggaatgaacaggcccgtgatggcttcaaagaatgataagctc
gagctgcaggactgcctggagttcagtaggacagcaaagttaaagaaagtgcagacaata
accaccaagtcgaactccatcagacagggcaaaaaccagcttttccctgtagtcatgaat
ggcaaggacgacgttttgtggtgcactgagctcgaaaggatcttcggcttccctgctcac
tacacggacgtgtccaacatgggccgcggcgcccgtcagaagctgctgggcaggtcctgg
agtgtaccggtcatcagacacctgtttgcccccttgaaggactactttgcctgtgaatag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (26)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (58)   
   RefSeq(nuc) (24)   
   GenBank (17)   
   EMBL (17)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (137)   

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